As a global leader in artificial skin manufacturing and a pioneer in the application of regenerative medicine and synthetic biology in China, the core founding team of Biohong Group has discovered through in-depth research on cell development, regeneration, and repair that the root cause of skin aging, dullness, redness, and swelling is cellular issues. Based on a profound understanding and specialized research of skin and cells, the group has successfully developed the groundbreaking "Dermal Targeting Specific Supramolecule Technology."
This series of technologies upgrades peptides, collagen, and nucleic acid ingredients, which are widely recognized as difficult to penetrate the skin, target, and deliver precisely. By employing interdisciplinary technical methods, these ingredients have been iterated into Peptide Microspheres, Collagen Microspheres and PDRN Microspheres, breaking through their application limitations and directly reaching target cells. This has achieved targeted enhancement of Peptide Microspheres, strong penetration of Collagen Microspheres, and precise anti-aging of PDRN Microspheres, allowing actives to penetrate to the cellular and organelle level, achieving true precision skincare, and bringing new ideas to the revolutionary upgrade of efficacy materials and precise skincare product solutions.
Peptides, collagen, and PDRN have been highly regarded for their outstanding efficacy, but their application in cosmetics is limited by issues such as stability, permeability, and targeting.
Biohong Group has simulated long-chain botulinum-like peptides using computer modeling, modified with myristoyl group to self-assemble into a stable spherical structure, giving it better permeability, stronger stability, and more significant anti-wrinkle and firming effects. This allows the peptides to increase dermal penetration by 393.14% at the 2-hour time point, significantly increasing collagen fiber content by 460%, and Type IV collagen content by 168%. Additionally, these Peptide Microspheres can carry other active ingredients, achieving intelligent assembly and intelligent dissociation for "multi-effect." For example, Peptide Microspheres combined with melittin form Melittin Microspheres, which can not only achieve precise anti-aging but also actively repair damaged and missing collagen in the body, as well as provide anti-inflammatory, soothing, and whitening effects.
Biohong Group, based on its self-developed recombinant human type III collagen, uses microspherization technology to compress extremely it into spherical collagen layer by layer with a particle size of less than 120 nanometers. This disruptive innovation not only greatly enhances the permeability and targeting of collagen but also more accurately replenishes the collagen needed by the skin, promoting cell repair and regeneration. It allows for rapid penetration into the skin, reaching the dermis in 0.5 hours, with an increased permeability rate of 255.14%.
PDRN, short for PolyDeoxyRiboNucleotide, has been widely used in skin regeneration and wound healing. Due to its poor stability and weak transdermal ability, it is often delivered to the dermis via microneedles or injections. Biohong Group employs its self-developed spherical PDRN technology to compress PDRN into nanoscale, overcoming the challenges of PDRN's difficulty in penetrating the skin and susceptibility to degradation. This allows it to rapidly penetrate the epidermis in 0.5 hours, with a 427.34% increase in dermal permeability after 1 hour, a 68% increase in DNA repair effects, and a 121% increase in collagen fiber content, enabling PDRN to rapidly penetrate cellular layers and precisely target damaged cells, repairing them and promoting collagen production.
The Biohong Group is launching precise cellular regulation skincare technology based on regenerative medicine to the world.
From regenerative medicine to precision skincare, Biohong Group, based on regenerative medicine, integrates the interdisciplinary advantages of cell biology, dermatology, synthetic biology, and materials science, continuously innovating in the field of precision skincare from cells to organelles. By regulating at the cellular level and reconstructing new efficacy material solutions, it opens a new chapter in precision skincare. On December 5, 2024, Biohong Group held the "Global Launch Conference of Dermal Targeting Specific Supramolecules (DTSS)" in Xi'an, China, where it launched its precision cell regulation achievement — the "Supramolecular Microsphere Technology," marking a revolutionary breakthrough in precision skincare and ushering in the era of precision cell regulation.
Media Contact
Company Name: Biohong Group
Contact Person: Wang Yidan
Email: Send Email
Country: China
Website: http://www.biohong.com/
