The U.S. military conducted "self-defense strikes" against Houthi missiles and a launcher prepared to fire from Yemen toward the Red Sea on Wednesday, U.S. Central Command announced.

Between 12 a.m. and 6:45 p.m. local time on Wednesday, four self-defense strikes were launched in response to seven mobile Houthi anti-ship cruise missiles and one mobile anti-ship ballistic missile launcher aimed at the Red Sea, the agency said.

Also, in an act of self-defense, CENTCOM said its forces shot down a one-way attack unmanned aircraft system.

US CARRIES OUT 'SELF-DEFENSE' STRIKE AGAINST HOUTHI ANTI-SHIP MISSILE: CENTCOM

The missiles, launchers and the unmanned aircraft system were all determined to have originated from Houthi-controlled areas of Yemen.

CENTCOM said they "presented an imminent threat to merchant vessels and to the U.S. Navy ships in the region" and were destroyed.

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"These actions will protect freedom of navigation and make international waters safer and more secure for U.S. Navy and merchant vessels," CENTCOM concluded.

CENTCOM and the State Department have been adamant in recent days about condemning Houthi aggression in the Red Sea toward military and civilian ships.

Prior to Wednesday's self-defense strikes, U.S. and coalition forces have shot down 11 one-way attack unmanned aerial vehicles, one anti-ship cruise missile, and one surface-to-air missile launcher located in Houthi-controlled Yemen since Feb. 19, according to CENTCOM announcements.

Fox News' Liz Friden contributed to this report.