Protein Enrichment Kits to Enable Deep Interrogation of Proteoforms through Protein Sequencing

Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced that it entered into a partnership with Aviva Systems Biology, a leading provider of antibody, protein, and immunoassay reagent products with an extensive portfolio of over 20,000 antibodies against more than 15,000 human gene targets. This partnership seeks to co-develop protein enrichment kits to enable deep interrogation of proteins of interest and their variants (proteoforms) through protein sequencing.

The co-developed products will include immunoprecipitation kits that fit into existing research workflows to conveniently enrich target proteins prior to amino acid mutation or post-translational modification (PTM) analysis with Quantum-Si’s Platinum^TM protein sequencing platform. This allows researchers to more efficiently and effectively uncover changes in proteins of interest and connect those changes to biological processes and disease.

"Biological processes, disease and health are ultimately attributed to protein function or dysfunction, and protein sequencing can support a greater understanding of these processes by unlocking biological insights at an unprecedented scale," said Jeff Hawkins, CEO of Quantum-Si. "We are committed to enabling existing research workflows with simple convenient solutions for proteomics research, and our partnership with Aviva Systems Biology will enable customers to conduct proteoform analysis in a simple and reproducible manner."

"This partnership brings together unique capabilities from Quantium-Si and Aviva Systems Biology that will accelerate new discoveries in protein research," said Kevin Harvey, President of Aviva. "Speeding up new discoveries is a shared goal at Quantum-Si and Aviva Systems Biology, and we are excited to partner with Quantum-Si to drive proteomics research forward."

About Quantum-Si Incorporated

Quantum-Si, The Protein Sequencing Company^TM, is focused on revolutionizing the growing field of proteomics. The Company's suite of technologies is powered by a first-of-its-kind semiconductor chip designed to enable next-generation single-molecule protein sequencing and digitize proteomic research in order to advance drug discovery and diagnostics beyond what has been possible with DNA sequencing. Learn more at www.quantum-si.com.

About Aviva Systems Biology

Aviva Systems Biology, founded in 2002, is a global market leader in proteomics research offering a broad portfolio of polyclonal and monoclonal antibodies, immunoassay kits, recombinant proteins, and custom protein expression and manufacturing services for academic and biopharma researchers. Headquartered in San Diego, California, Aviva’s offering supports multiple applications including western blotting, IHC, ELISA, and immunoprecipitation along with providing researchers one of the largest catalogs of targets and species to choose from. Learn more at www.avivasysbio.com.

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