ProtoKinetix, Incorporated (www.protokinetix.com) (the "Company" or "ProtoKinetix") (OTCQB: PKTX), a clinical-stage biomedical company, today announced that the University of Alberta has successfully completed Phase 1 clinical trial enrollment for the treatment of type 1 diabetes in islet cell transplants. The molecule, PKX-001 (AAGP®) successfully achieved, to date, the primary safety objectives. The trial is continuing with observation of the latest enrolled patients to monitor secondary objectives over the next 6-months. Following this period of follow-up, all secondary objectives will have been evaluated in all patients, and the data will be collated, analyzed, and reported.

The trial is being led by Dr. James Shapiro, MD, PhD, FRCSC, MSM FCAHS, AHS Director of Clinical Islet, Liver Transplant and Living Donor Liver Transplant Programs, Canada Research Chair in Transplant Surgery and Regenerative Medicine, Professor of Surgery, Medicine and Surgical Oncology, University of Alberta.

“We are excited to move forward with dose escalation in this exciting trial using this anti-aging glyopeptide molecule AAGP, and eagerly await data on how this might improve and protect islets after transplant. Certainly, at this point the data shows the molecule is safe” - Dr. James Shapiro.

Dr. James Shapiro Bio

To obtain additional information and monitor updates regarding this trial please use the following link: Clinicaltrials.gov – Islet Transplantation Using PKX-001.

About ProtoKinetix, Incorporated

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