SECURITIES EXCHANGE COMMISSION
Washington, DC 20549
Under the Securities Exchange Act of 1934
(Amendment No. 2)
LIGAND PHARMACEUTICALS, INC.
(Name of Issuer)
Common
(Title of Class of Securities)
Date of Event Which Requires Filing of this Statement
December 31, 2003
Check the appropriate box to designate the rule
pursuant to which this Schedule is filed
[ ] Rule 13d-1(b)
[X] Rule 13d-1(c)
[ ] Rule 13d-1(d)
53220K207
(CUSIP NUMBER)
1) Name of Reporting Pioneer Global Asset
Person Management S.p.A.
IRS Identification 13-1961193
No. of Above
2) Check the Appropriate Box (a)
of A Member of Group
(See Instructions) (b) X
3) SEC Use Only
4) Citizenship of Place of
Organization Italy
Number of (5) Sole Voting 3,928,270
Shares Power
Beneficially Owned (6) Shared Voting 0
by Each Reporting Power
Person With (7) Sole Disposi- 3,928,270
tive Power
(8) Shared Dispo- 0
sitive Power
9) Aggregate Amount Beneficially 3,928,270
Owned by Each
Reporting Person
10) Check if the aggregate Amount in Row (9) Exclude Certain Shares (See
Instructions)
11) Percent of Class Represented
By Amount in Row 9. 5.10%
12) Type of Reporting
Person (See Instructions) IA
Item 1(a) Name of Issuer.
LIGAND PHARMACEUTICALS, INC.
Item 1(b) Address of Issuer's Principal Executive Offices:
10275 Science Center Drive
San Diego, CA 92121
Item 2(a) Name of Person Filing:
Pioneer Global Asset Management S.p.A.
Item 2(b) Address of Principal Business Office:
6 Galleria San Carlo 6
20122 Milan, Italy
Item 2(c) Citizenship:
Italy
Item 2(d) Title of Class of Securities:
Common Stock
Item 2(e) CUSIP Number:
53220K207
Item 3 The person filing this statement pursuant to Rule 13d-1(b)
or 13d-2(b) is:
Inapplicable
Item 4. Ownership.
(a) Amount Beneficially Owned: 3,928,270
(b) Percent of Class: 5.10%
(c) Number of shares as to which such person has
(i) sole power to vote or to direct the vote 3,928,270 (ii) shared
power to vote or to direct vote 0
(iii) sole power to dispose or to direct disposition of 3,928,270
(iv) shared power to dispose or to direct disposition 0
Item 5. Ownership of Five Percent or Less of a Class.
If this statement is being filed to report the fact that as of the date
Hereof the reporting person has ceased to be the beneficial owner of
more than five percent of the class of securities, check here:
Item 6. Ownership of More than Five Percent on Behalf of Another Person.
Inapplicable.
Item 7. Identification and Classification of the Subsidiary Which Acquired
the Security Being Reported On By the Parent Holding Company.
Inapplicable.
Item 8. Identification and Classification of Members of the Group.
Inapplicable.
Item 9. Notice of Dissolution of the Group.
Inapplicable.
Item 10. Certification.
By signing below I certify that, to the best of my knowledge and belief, the
securities referred to above were acquired in the ordinary course of business
and were not acquired for the purpose of and do not have the effect of changing
or influencing the control of the issuer of such securities and were not
acquired in connection with or as a participant in any transactions having such
purposes or effect.
After reasonable inquiry and to the best of my knowledge and believe, I certify
that the information set forth in this statement is true, complete and correct.
February 10, 2004
Date
/s/Dario Frigerio
Dario Frigerio
Chief Executive Officer