PAGE 1
000 A000000 11/30/2008
000 C000000 0001380936
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 6.1
000 J000000 A
001 A000000 CLAYMORE/GUGGENHEIM STRATEGIC OPP FUND
001 B000000 811-21982
001 C000000 6305053700
002 A000000 2455 CORPORATE WEST DRIVE
002 B000000 LISLE
002 C000000 IL
002 D010000 60532
003 000000 N
004 000000 N
005 000000 N
006 000000 N
007 A000000 N
007 B000000 0
007 C010100 1
007 C010200 2
007 C010300 3
007 C010400 4
007 C010500 5
007 C010600 6
007 C010700 7
007 C010800 8
007 C010900 9
007 C011000 10
008 A000001 CLAYMORE ADVISORS, LLC
008 B000001 A
008 C000001 801-000000
008 D010001 LISLE
008 D020001 IL
008 D030001 60532
008 A000002 GUGGENHEIM PARTNERS ASSET MANAGEMENT, INC.
008 B000002 S
008 C000002 801-000000
008 D010002 SANTA MONICA
008 D020002 CA
008 D030002 90401
010 A000001 CLAYMORE ADVISORS, LLC
010 B000001 84-0000000
010 C010001 LISLE
010 C020001 IL
010 C030001 60532
011 A000001 WACHOVIA CAPITAL MARKETS LLC
011 B000001 8-00000000
PAGE 2
011 C010001 CHARLOTTE
011 C020001 NC
011 C030001 28288
011 A000002 RAYMOND JAMES & ASSOCIATES, INC.
011 B000002 8-00000000
011 C010002 ST. PETERSBURG
011 C020002 FL
011 C030002 33716
012 A000001 THE BANK OF NEW YORK MELLON
012 B000001 84-0000000
012 C010001 NEW YORK
012 C020001 NY
012 C030001 10286
013 A000001 ERNST & YOUNG LLP
013 B010001 CHICAGO
013 B020001 IL
013 B030001 60606
015 A000001 THE BANK OF NEW YORK
015 B000001 C
015 C010001 NEW YORK
015 C020001 NY
015 C030001 10286
015 E010001 X
018 000000 Y
019 A000000 N
019 B000000 0
020 A000001 GOLDMAN SACHS & COMPANY
020 B000001 13-5108880
020 C000001 69
020 A000002 JPMORGAN CHASE & CO.
020 B000002 13-2624428
020 C000002 12
020 A000003 BANK OF AMERICA
020 B000003 56-0906609
020 C000003 8
020 A000004 MERRILL LYNCH & COMPANY, INC.
020 B000004 13-2740599
020 C000004 7
020 A000005 NBP PARIBAS BROKERAGE, INC.
020 B000005 N/A
020 C000005 2
020 A000006 MONTGOMERY SECURITIES
020 B000006 94-1701676
020 C000006 0
020 C000007 0
020 C000008 0
020 C000009 0
020 C000010 0
021 000000 99
022 A000001 BANK OF AMERICA
022 B000001 56-0906609
PAGE 3
022 C000001 100388
022 D000001 6598
022 A000002 LEHMAN BROTHERS HOLDINGS, INC.
022 B000002 13-3216325
022 C000002 59747
022 D000002 40924
022 A000003 MONTGOMERY SECURITIES
022 B000003 94-1701676
022 C000003 88768
022 D000003 1443
022 A000004 GOLDMAN SACHS & CO.
022 B000004 13-5108880
022 C000004 3543
022 D000004 71619
022 A000005 MERRILL LYNCH & CO., INC.
022 B000005 13-2740599
022 C000005 42261
022 D000005 57498
022 A000006 MORGAN STANLEY & CO., INC.
022 B000006 13-2655998
022 C000006 36312
022 D000006 34905
022 A000007 BARCLAYS CAPITAL, INC.
022 B000007 06-1031656
022 C000007 39912
022 D000007 16125
022 A000008 JPMORGAN CHASE & CO.
022 B000008 13-2624428
022 C000008 20597
022 D000008 26112
022 A000009 CS FIRST BOSTON CORP.
022 B000009 13-5659485
022 C000009 26569
022 D000009 8903
022 A000010 WARBURG DILLON READ
022 B000010 N/A
022 C000010 35047
022 D000010 0
023 C000000 570262
023 D000000 413799
024 000000 Y
025 A000001 MUZINICH CBO II LTD.
025 B000001 N/A
025 C000001 D
025 D000001 1528
025 A000002 MERNA REINSURANCE LTD.
025 B000002 N/A
025 C000002 D
025 D000002 1853
025 A000003 HAMPTON ROADS PPV LLC
025 B000003 N/A
PAGE 4
025 C000003 D
025 D000003 1508
025 A000004 ROYAL BANK OF SCOTLAND GROUP PLC
025 B000004 N/A
025 C000004 D
025 D000004 676
025 A000005 DEUTSCHE BANK CONTINGENT CAPITAL TRUST II
025 B000005 N/A
025 C000005 E
025 D000005 659
025 A000006 BNP PARIBAS
025 B000006 N/A
025 C000006 D
025 D000006 720
025 A000007 PROGRESSIVE CORP (THE)
025 B000007 34-0963169
025 C000007 D
025 D000007 664
025 A000008 SANTANDER FINANCE PREFERRED SA UNIPERSONAL
025 B000008 N/A
025 C000008 E
025 D000008 747
025 A000009 COBANK, ACB
025 B000009 84-1102254
025 C000009 D
025 D000009 959
025 A000010 FIFTH THIRD BANCORP
025 B000010 31-0854434
025 C000010 D
025 D000010 787
025 A000011 MELLON CAPITAL IV
025 B000011 N/A
025 C000011 D
025 D000011 751
025 A000012 WELLS FARGO CAPITAL XIII
025 B000012 N/A
025 C000012 D
025 D000012 811
025 A000013 KEYBANK NA
025 B000013 34-0797057
025 C000013 D
025 D000013 828
025 A000014 TORCHMARK CAPITAL TRUST III
025 B000014 N/A
025 C000014 E
025 D000014 700
025 A000015 STATE STREET CAPITAL TRUST IV
025 B000015 N/A
025 C000015 D
025 D000015 702
025 A000016 KEYCORP CAPITAL III
PAGE 5
025 B000016 N/A
025 C000016 D
025 D000016 704
025 A000017 AGUA CALIENTE BAND OF CAHUILLA INDIANS
025 B000017 N/A
025 C000017 D
025 D000017 889
025 A000018 US AGBANK FCB
025 B000018 52-1578738
025 C000018 D
025 D000018 786
025 A000019 AGFIRST FARM CREDIT BANK
025 B000019 52-1578738
025 C000019 D
025 D000019 886
025 A000020 BARCLAYS BANK PLC
025 B000020 13-4075851
025 C000020 D
025 D000020 702
025 A000021 DELETE
025 D000021 0
025 A000022 DELETE
025 D000022 0
025 A000023 DELETE
025 D000023 0
025 A000024 DELETE
025 D000024 0
025 A000025 DELETE
025 D000025 0
025 A000026 DELETE
025 D000026 0
025 A000027 DELETE
025 D000027 0
025 A000028 DELETE
025 D000028 0
025 A000029 DELETE
025 D000029 0
025 A000030 DELETE
025 D000030 0
025 D000031 0
025 D000032 0
026 A000000 N
026 B000000 Y
026 C000000 N
026 D000000 Y
026 E000000 N
026 F000000 N
026 G010000 N
026 G020000 N
026 H000000 N
027 000000 N
PAGE 6
028 A010000 0
028 A020000 0
028 A030000 0
028 A040000 0
028 B010000 0
028 B020000 0
028 B030000 0
028 B040000 0
028 C010000 0
028 C020000 0
028 C030000 0
028 C040000 0
028 D010000 0
028 D020000 0
028 D030000 0
028 D040000 0
028 E010000 0
028 E020000 0
028 E030000 0
028 E040000 0
028 F010000 0
028 F020000 0
028 F030000 0
028 F040000 0
028 G010000 0
028 G020000 0
028 G030000 0
028 G040000 0
028 H000000 0
030 A000000 0
030 B000000 0.00
030 C000000 0.00
031 A000000 0
031 B000000 0
032 000000 0
033 000000 0
035 000000 0
036 B000000 0
038 000000 0
042 A000000 0
042 B000000 0
042 C000000 0
042 D000000 0
042 E000000 0
042 F000000 0
042 G000000 0
042 H000000 0
043 000000 0
044 000000 0
045 000000 Y
046 000000 N
PAGE 7
047 000000 Y
048 000000 1.000
048 A010000 0
048 A020000 0.000
048 B010000 0
048 B020000 0.000
048 C010000 0
048 C020000 0.000
048 D010000 0
048 D020000 0.000
048 E010000 0
048 E020000 0.000
048 F010000 0
048 F020000 0.000
048 G010000 0
048 G020000 0.000
048 H010000 0
048 H020000 0.000
048 I010000 0
048 I020000 0.000
048 J010000 0
048 J020000 0.000
048 K010000 0
048 K020000 0.000
049 000000 N
050 000000 N
051 000000 N
052 000000 N
053 A000000 N
054 A000000 Y
054 B000000 Y
054 C000000 N
054 D000000 N
054 E000000 N
054 F000000 N
054 G000000 N
054 H000000 Y
054 I000000 N
054 J000000 Y
054 K000000 N
054 L000000 N
054 M000000 Y
054 N000000 N
054 O000000 N
055 A000000 Y
055 B000000 N
056 000000 N
057 000000 N
058 A000000 N
059 000000 Y
060 A000000 Y
PAGE 8
060 B000000 Y
061 000000 0
062 A000000 Y
062 B000000 0.0
062 C000000 0.0
062 D000000 0.0
062 E000000 0.0
062 F000000 0.0
062 G000000 0.0
062 H000000 0.0
062 I000000 0.0
062 J000000 0.0
062 K000000 0.0
062 L000000 0.0
062 M000000 0.0
062 N000000 8.6
062 O000000 0.0
062 P000000 27.5
062 Q000000 84.0
062 R000000 24.6
063 A000000 0
063 B000000 17.9
064 A000000 N
064 B000000 N
066 A000000 N
067 000000 N
068 A000000 N
068 B000000 N
069 000000 N
070 A010000 Y
070 A020000 Y
070 B010000 Y
070 B020000 Y
070 C010000 Y
070 C020000 N
070 D010000 Y
070 D020000 Y
070 E010000 Y
070 E020000 Y
070 F010000 Y
070 F020000 Y
070 G010000 Y
070 G020000 Y
070 H010000 Y
070 H020000 Y
070 I010000 N
070 I020000 N
070 J010000 Y
070 J020000 Y
070 K010000 Y
070 K020000 N
PAGE 9
070 L010000 Y
070 L020000 Y
070 M010000 Y
070 M020000 N
070 N010000 Y
070 N020000 N
070 O010000 Y
070 O020000 Y
070 P010000 Y
070 P020000 N
070 Q010000 N
070 Q020000 N
070 R010000 Y
070 R020000 Y
071 A000000 153469
071 B000000 67138
071 C000000 190857
071 D000000 35
072 A000000 6
072 B000000 6342
072 C000000 363
072 D000000 0
072 E000000 0
072 F000000 990
072 G000000 27
072 H000000 0
072 I000000 10
072 J000000 20
072 K000000 0
072 L000000 31
072 M000000 33
072 N000000 14
072 O000000 0
072 P000000 925
072 Q000000 70
072 R000000 31
072 S000000 34
072 T000000 0
072 U000000 0
072 V000000 0
072 W000000 54
072 X000000 2239
072 Y000000 0
072 Z000000 4466
072AA000000 0
072BB000000 4565
072CC010000 0
072CC020000 10093
072DD010000 8413
072DD020000 0
072EE000000 0
PAGE 10
073 A010000 0.9200
073 A020000 0.0000
073 B000000 0.0000
073 C000000 0.0000
074 A000000 0
074 B000000 0
074 C000000 0
074 D000000 132924
074 E000000 4098
074 F000000 655
074 G000000 0
074 H000000 0
074 I000000 22417
074 J000000 0
074 K000000 0
074 L000000 1589
074 M000000 2756
074 N000000 164439
074 O000000 0
074 P000000 6010
074 Q000000 0
074 R010000 21913
074 R020000 0
074 R030000 4070
074 R040000 21822
074 S000000 0
074 T000000 110624
074 U010000 9105
074 U020000 0
074 V010000 12.15
074 V020000 0.00
074 W000000 0.0000
074 X000000 7076
074 Y000000 90017
075 A000000 0
075 B000000 141420
076 000000 10.15
077 A000000 N
078 000000 N
080 C000000 0
081 B000000 0
082 B000000 0
083 B000000 0
084 B000000 0
086 A010000 0
086 A020000 0
086 B010000 0
086 B020000 0
086 C010000 0
086 C020000 0
086 D010000 0
PAGE 11
086 D020000 0
086 E010000 0
086 E020000 0
086 F010000 0
086 F020000 0
087 A010000 COMMON STOCK
087 A020000 18385X104
087 A030000 GOF
088 A000000 Y
088 B000000 N
088 C000000 N
088 D000000 Y
SIGNATURE STEVEN M. HILL
TITLE CFO & TREASURER