Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
SHELTON JERRELL
   2. Issuer Name and Ticker or Trading Symbol
Cryoport, Inc. [CYRX] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chief Executive Officer
(Last)
(First)
(Middle)
980 OVERTON LEA ROAD		 3. Date of Earliest Transaction (Month/Day/Year)
06/12/2018
(Street)

NASHVILLE, TN 37220		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 06/12/2018   M   2,938 A $ 1.87 279,539 D  
Common Stock 06/12/2018   M   1,300 A $ 4.8 280,839 D  
Common Stock 06/12/2018   M   20,000 A $ 5 300,839 D  
Common Stock 06/12/2018   X   5,001 A $ 5.88 305,840 D  
Common Stock 06/12/2018   S(1)   2,252 D $ 13.06 303,588 D  

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option to Purchase Common Stock $ 1.87 06/12/2018   M     2,938   (2) 05/06/2026 Common Stock 2,938 $ 0 255,524 D  
Option to Purchase Common Stock $ 4.8 06/12/2018   M     1,300   (3) 12/18/2024 Common Stock 1,300 $ 0 369,700 D  
Option to Purchase Common Stock $ 5 06/12/2018   M     20,000   (4) 08/19/2025 Common Stock 20,000 $ 0 807,000 D  
Warrant to Purchase Common Stock $ 5.88 06/12/2018   X     5,001   (5) 12/31/2018 Common Stock 5,001 $ 0 0 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
SHELTON JERRELL
980 OVERTON LEA ROAD
NASHVILLE, TN 37220		   X     Chief Executive Officer  

Signatures

 /s/ Jerrell Shelton   06/14/2018
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The reporting person exercised a warrant to purchase 5,001 shares for $5.88 per share. The reporting person paid the exercise price on a cashless basis, resulting in the Company's withholding of 2,749 shares to pay the exercise price and issuing to the reporting person the remaining 2,252 shares.
(2) 1/48 of the 280,000 options originally granted vest on the 6th of each month for forty-eight months beginning on May 6, 2016.
(3) 1/48 of the 387,501 options originally granted vest on the 18th of each month for forty-eight months beginning on January 18, 2015.
(4) 1/48 of the 827,000 options originally granted vest on the 19th of each month for forty-eight months beginning on August 19, 2015.
(5) Warrants to purchase 2,917 shares were exercisable on December 11, 2013 and warrants to purchase 2,084 shares were exercisable on January 10, 2014, in each case, the date of issuance.

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